Article
A consistent two-mutation model of lung cancer for different data sets of radon-exposed rats.
Radiation and environmental biophysics - 1 Dec 2001
Bijwaard H, Brugmans M J, Leenhouts H P
Abstract excerpt
A two-mutation carcinogenesis model, formulated in terms of biologically motivated equations for mutation and expansion steps, has been applied in a mechanistic modelling of the lung cancer incidence in two large data sets of rats exposed to radon, both separately and jointly. Results indicate that (1) the equations employed are able to provide an accurate description of the separate data sets, (2) the parameters...
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