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Article

Significance of DNA adducts at low dose: shortening the time to spontaneous tumor occurrence.

Regulatory toxicology and pharmacology : RTP - 1 Feb 1996

Lutz W K, Gaylor D

Abstract excerpt

Formation and repair of adducts from DNA-reactive carcinogens as well as induction of genetic changes is expected to be proportional to dose as long as the rates of the enzymatic reactions are proportional to the substrate concentration and as long as the kinetics of cell division are not affected. Deviations from linearity are expected in situations of saturated or induced kinetics and whenever toxicity...

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Source

Identifiers

PMID: 8628917
DOI: 10.1006/rtph.1996.0005

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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