Article
Clonal evolution of lung tumors.
Cancer research - 1 Apr 1996
Chung G T, Sundaresan V, Hasleton P, Rudd R, Taylor R, Rabbitts P H
Abstract excerpt
Lung tumors, particularly squamous cell carcinomas, are believed to develop through a series of morphological abnormalities, driven by underlying somatic genetic changes. One way of studying this process is to analyze candidate somatic genetic changes in samples of squamous metaplasia and bronchial dysplasia of varying degrees of severity as well as tumor from the same patient. This assumes a clonal relationship...
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