[Characteristics of mutants induced by the c-Ha-ras1 oncogene and the nature of the oncogene's mutagenic action].

Article

[Characteristics of mutants induced by the c-Ha-ras1 oncogene and the nature of the oncogene's mutagenic action].

Genetika - 1 Dec 1995

Bobrysheva I V, Varshaver N B

Abstract excerpt

Chinese hamster cell clones of independent origin, which were resistant to purine base analogs and induced by the activated c-Ha-ras1 oncogene, were isolated. It was shown that the isolated clones stably retained resistance after cultivation on a medium without an analog, confirming mutational na...

Topics

Animals
Cells, Cultured
Cricetinae
Cricetulus
Genes, ras
Humans
Hypoxanthine Phosphoribosyltransferase
Mutation
Nucleic Acid Hybridization

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