Article
[The plasmid pEJ6.6 carrying the activated c-Ha-ras-1 oncogene increases the mutation frequency in Chinese hamster cells].
Genetika - 1 Jun 1992
Baron E M, Bobrysheva I V, Varshaver N B
Abstract excerpt
The induction of gene mutations and chromosome aberrations by the plasmid pEJ6.6 carrying the activated c-Ha-ras-1 oncogene from human bladder carcinoma was studied in cultured Chinese hamster cells. Both an increase in the frequency of gene mutations to 6-mercaptopurine resistance and of chromosome aberrations was observed after pEJ6.6 treatment as compared to control series (pBR322). Thus the results of...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.