The gonadotropin-releasing hormone system does not develop in Small-Eye (Sey) mouse phenotype.

doi:10.1016/s0165-3806(98)00007-8

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Article

The gonadotropin-releasing hormone system does not develop in Small-Eye (Sey) mouse phenotype.

Brain research. Developmental brain research - 15 May 1998

Dellovade T L, Pfaff D W, Schwanzel-Fukuda M

Abstract excerpt

This study examined the development of the gonadotropin releasing-hormone (GnRH) system in a spontaneous mouse mutation, Small-Eye (Sey). This phenotype is due to a point mutation in the developmental control gene Pax-6 and results in failed development of the eye and olfactory placodes in homozy...

Topics

Alleles
Animals
Eye
Eye Abnormalities
Female
Gonadotropin-Releasing Hormone
Immunohistochemistry
Mice
Mice, Neurologic Mutants
Neural Cell Adhesion Molecules
Phenotype
Pregnancy

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