Article
Epigenetic effects on yeast transcription caused by mutations in an actin-related protein present in the nucleus.
Genes & development - 1 Mar 1996
Jiang Y W, Stillman D J
Abstract excerpt
Gene inactivation can result when a delta element of the Ty1 transposon inserted into the yeast HIS4 promoter (his4-912delta) alters the transcription initiation site. Previous work has identified mutations that suppress this transcriptional defect by restoring the transcription start site to the native position, and these mutations have been implicated in transcriptional regulation and chromatin structure. We...
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