Article
A neural tetraspanin, encoded by late bloomer, that facilitates synapse formation.
Science (New York, N.Y.) - 29 Mar 1996
Kopczynski C C, Davis G W, Goodman C S
Abstract excerpt
Upon contacting its postsynaptic target, a neuronal growth cone transforms into a presynaptic terminal. A membrane component on the growth cone that facilitates synapse formation was identified by means of a complementary DNA-based screen followed by genetic analysis. The late bloomer (lbl) gene...
Topics
- Amino Acid Sequence
- Animals
- Axons
- Cloning, Molecular
- Drosophila
- Drosophila Proteins
- Genes, Insect
- Membrane Proteins
- Molecular Sequence Data
- Motor Neurons
- Muscles
- Mutation
- Nerve Tissue Proteins
- Neuromuscular Junction
- Presynaptic Terminals
- Signal Transduction