Article
Bruchpilot in ribbon-like axonal agglomerates, behavioral defects, and early death in SRPK79D kinase mutants of Drosophila.
PLoS genetics - 1 Oct 2009
Nieratschker Vanessa, Schubert Alice, Jauch Mandy, Bock Nicole, Bucher Daniel, Dippacher Sonja, Krohne Georg, Asan Esther, Buchner Sigrid, Buchner Erich
Abstract excerpt
Defining the molecular structure and function of synapses is a central theme in brain research. In Drosophila the Bruchpilot (BRP) protein is associated with T-shaped ribbons ("T-bars") at presynaptic active zones (AZs). BRP is required for intact AZ structure and normal evoked neurotransmitter r...
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