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Article

The fibrinolytic activity of staphylokinase mutants in the fibrin plate assay.

Haemostasis - 1 Jan 2000

Hauptmann J, Gührs K H, Hartmann M, Schlott B

Abstract excerpt

The fibrinolytic activity of the new plasminogen activator, recombinant staphylokinase, was compared to that of streptokinase and tissue-type plasminogen activator in the fibrin plate assay. The pattern of fibrinolysis by staphylokinase on fibrin plates differs from the other plasminogen activators. A number of mutants of staphylokinase with various amino acids in position 26 substituted for methionine in...

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Identifiers

PMID: 8586317
DOI: 10.1159/000217172

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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The fibrinolytic activity of staphylokinase mutants in the fibrin plate assay.PMID 8586317Read ↗

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Mutation of lysines in a plasminogen binding region of streptokinase identifies residues important for generating a functional activator complex.Semantic proximity Read ↗

Staphylokinase Requires NH2-terminal Proteolysis for Plasminogen ActivationSemantic proximity Read ↗

High resolution analysis of functional determinants on human tissue-type plasminogen activator.Semantic proximity Read ↗

Biochemical and Immunological Properties of Engineered Low-Immunogenic Staphylokinases for Next-Generation Thrombolytic TherapySemantic proximity Read ↗

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