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Article

Functional properties of a novel mutant of staphylokinase with platelet-targeted fibrinolysis and antiplatelet aggregation activities.

European journal of pharmacology - 2 Jul 2007

Chen Hongshan, Mo Wei, Zhang Yanling, Su Huabo, Ma Janying, Yao Ruiming, Zhang Shaoheng, Ge Junbo, Song Houyan

Abstract excerpt

The present study was performed to characterize the functional properties of RGD-SAK, a novel mutant of staphylokinase (SAK). Biochemical analysis indicated that RGD-SAK maintained the similar structure and the fibrinolytic function of SAK. Measurement of platelet binding activity in vitro demons...

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Source

Identifiers

PMID: 17451675
DOI: 10.1016/j.ejphar.2007.03.010

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17451675-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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