Article
Mutation accumulation in transfer RNAs: molecular evidence for Muller's ratchet in mitochondrial genomes.
Molecular biology and evolution - 1 Jan 1996
Lynch M
Abstract excerpt
The accumulation of deleterious mutations is thought to be a major factor preventing the long-term persistence of obligately asexual lineages relative to their sexual ancestors. This phenomenon is also of potential relevance to sexual species that harbor asexually propagating organelle genomes. A...
Topics
- Animals
- DNA, Mitochondrial
- Evolution, Molecular
- Models, Theoretical
- Mutation
- RNA, Transfer