Article
Dimerization of small GTPase Rab5.
International journal of molecular medicine - 1 Oct 2001
Daitoku H, Isida J, Fujiwara K, Nakajima T, Fukamizu A
Abstract excerpt
Rab proteins are small GTPases, localized to distinct cellular compartments, regulating specific steps of intracellular membrane trafficking. One member of the Rab family, Rab5, consists of three isoforms, Rab5a, Rab5b, and Rab5c, which have been shown to play an important role in early events of endocytosis. Using the yeast two-hybrid system, we have identified several cytosolic proteins that interact with the...
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