Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Receptor and membrane recycling can occur with unaltered efficiency despite dramatic Rab5(q79l)-induced changes in endosome geometry.

The Journal of biological chemistry - 30 Mar 2001

Ceresa B P, Lotscher M, Schmid S L

Abstract excerpt

Current models for sorting in the endosomal compartment suggest that endosomal geometry plays a significant role as membrane-bound proteins accumulate in tubular regions for recycling, and lumenal markers accumulate in large vacuolar portions for delivery to lysosomes. Rab5, a small molecular weight GTPase, functions in the formation and maintenance of the early/sorting endosome. Overexpression of the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adenoviridae
Share to Endocytosis
Share to Endosomes

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to GTP Phosphohydrolases

Share to rab5 GTP-Binding Proteins

Share to Receptors, Transferrin

Share to Tetracycline

Share to Transferrin

Source

Identifiers

PMID: 11136733
DOI: 10.1074/jbc.M010387200

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Receptor and membrane recycling can occur with unaltered efficiency despite dramatic Rab5(q79l)-induced changes in endosome geometry.PMID 11136733Read ↗

Early endocytic Rabs: functional prediction to functional characterization.Semantic proximity Read ↗

The Endosomal Recycling Pathway—At the Crossroads of the CellSemantic proximity Read ↗

Expression of dominant negative rab5 in HeLa cells regulates endocytic trafficking distal from the plasma membrane.Semantic proximity Read ↗

Vesicular trafficking: molecular tools and targets.Semantic proximity Read ↗

Continual expression of Rab5(Q79L) causes a ligand-independent EGFR internalization and diminishes EGFR activity.Semantic proximity Read ↗

A targeted RNAi screen identifies factors affecting diverse stages of receptor-mediated transcytosis.Semantic proximity Read ↗

Characterization of Rab5:Q79L-stimulated endosome fusion.Semantic proximity Read ↗

Regulation of endocytosis by the small GTP-ase rab5.Semantic proximity Read ↗

Rab15 mediates an early endocytic event in Chinese hamster ovary cells.Semantic proximity Read ↗

Rab15 differentially regulates early endocytic trafficking.Semantic proximity Read ↗

Rab15 Differentially Regulates Early Endocytic TraffickingSemantic proximity Read ↗

Rab10 GTPase regulates ER dynamics and morphology.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.