Article
Hepatitis C virus genotyping by means of 5'-UR/core line probe assays and molecular analysis of untypeable samples.
Virus research - 1 Oct 1995
Stuyver L, Wyseur A, van Arnhem W, Lunel F, Laurent-Puig P, Pawlotsky J M, Kleter B, Bassit L, Nkengasong J, van Doorn L J
Abstract excerpt
To test the theoretical possibility of 5'-UR mistyping between hepatitis C virus subtypes 1a and 1b, we combined a 5'-UR/Core line probe assay (LiPA) with a nested PCR system and retested 183 sera, previously genotyped as type 1a or 1b and originating mainly from Western Europe. Eight percent of these were found to be wrongly subtyped. Based on this method, 3 additional subtypes of type 1 were discovered (1d-1f)....
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