Article
Comparison of line probe assay and DNA sequencing of 5' untranslated region for genotyping hepatitis C virus: description of novel line probe patterns.
Diagnostic microbiology and infectious disease - 1 Mar 2002
Mitchell P Shawn, Sloan Lynne M, Majewski David W, Rys Paul N, Heimgartner Paul J, Rosenblatt Jon E, Cockerill Franklin R, Smith Thomas F, Patel Robin
Abstract excerpt
We compared a commercial line probe assay (INNO-LiPA HCV II, Innogenetics, N.V., Ghent, Belgium, distributed by Bayer Diagnostics) to an in-house 5' untranslated region direct DNA sequencing method for genotyping hepatitis C virus (HCV). Initial evaluation demonstrated that the INNO-LiPA HCV II assay and sequencing assay assigned the same genotype for 110/132 (83.3%) patient specimens (98 subtype and 12 genotype...
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