Article
Hepatitis C virus subtyping based on sequencing of the C/E1 and NS5B genomic regions in comparison to a commercially available line probe assay.
Journal of medical virology - 1 May 2013
Avó Ana Patrícia, Agua-Doce Ivone, Andrade Ana, Pádua Elizabeth
Abstract excerpt
Hepatitis C virus (HCV) genotype determination is required in clinical practice to establish the dose and duration of antiviral treatment. Although subtype identification does not impact on current therapy this is changing with new specific inhibitors of HCV enzymes and functions which are becoming available worldwide. These new drugs may yield different antiviral responses and resistance profiles. Accurate...
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