Article
Typing of hepatitis C virus isolates and characterization of new subtypes using a line probe assay.
The Journal of general virology - 1 Jun 1993
Stuyver L, Rossau R, Wyseur A, Duhamel M, Vanderborght B, Van Heuverswyn H, Maertens G
Abstract excerpt
A reverse-hybridization assay, the line probe assay (LiPA), based on variations found in the 5' untranslated regions of the different hepatitis C virus (HCV) genotypes was developed, permitting simple and fast determination of four HCV genotypes and their subtypes. Using this assay, 61 PCR-positi...
Topics
- Base Sequence
- DNA Probes
- DNA, Viral
- Genetic Variation
- Hepacivirus
- Hepatitis C
- Humans
- Molecular Sequence Data
- Nucleic Acid Hybridization
- Polymerase Chain Reaction
- Sensitivity and Specificity
- Sequence Homology, Nucleic Acid
- Serotyping
- Terminology as Topic