Article
Hepatitis C virus (HCV) genotype 1 subtype identification in new HCV drug development and future clinical practice.
PloS one - 8 Dec 2009
Chevaliez Stéphane, Bouvier-Alias Magali, Brillet Rozenn, Pawlotsky Jean-Michel
Abstract excerpt
BACKGROUND: With the development of new specific inhibitors of hepatitis C virus (HCV) enzymes and functions that may yield different antiviral responses and resistance profiles according to the HCV subtype, correct HCV genotype 1 subtype identification is mandatory in clinical trials for stratification and interpretation purposes and will likely become necessary in future clinical practice. The goal of this...
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