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Article

The gene virilizer is required for female-specific splicing controlled by Sxl, the master gene for sexual development in Drosophila.

Development (Cambridge, England) - 1 Dec 1995

Hilfiker A, Amrein H, Dübendorfer A, Schneiter R, Nöthiger R

Abstract excerpt

The gene virilizer (vir) is needed for dosage compensation and sex determination in females and for an unknown vital function in both sexes. In genetic mosaics, XX somatic cells mutant for vir differentiate male structures. One allele, vir2f, is lethal for XX, but not for XY animals. This female-specific lethality can be rescued by constitutive expression of Sxl or by mutations in msl (male-specific lethal)...

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PMID: 8575302
DOI: 10.1242/dev.121.12.4017

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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The gene virilizer is required for female-specific splicing controlled by Sxl, the master gene for sexual development in Drosophila.PMID 8575302Read ↗

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