Article
Functional conservation of the sex-lethal sex determining promoter, Sxl-Pe, in Drosophila virilis.
Development genes and evolution - 1 May 2003
Jinks Timothy Morgan, Calhoun Gretchen, Schedl Paul
Abstract excerpt
The primary sex determination signal in Drosophila melanogaster, the ratio of X chromosomes to autosomes, sets the activity state of the switch gene, Sex-lethal ( Sxl), by regulating the establishment promoter, m-Sxl-Pe. We have identified and characterized the establishment promoter, v-Sxl-Pe, of the distantly related species Drosophila virilis. Like melanogaster, the virilis Sxl-Pe is organized into four...
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