Article
Interaction of the unique N-terminal region of tyrosine kinase p56lck with cytoplasmic domains of CD4 and CD8 is mediated by cysteine motifs.
Cell - 9 Mar 1990
Turner J M, Brodsky M H, Irving B A, Levin S D, Perlmutter R M, Littman D R
Abstract excerpt
p56lck, a lymphocyte-specific member of the src family of cytoplasmic protein-tyrosine kinases, is associated noncovalently with the cell surface glycoproteins CD4 and CD8, which are expressed on functionally distinct subpopulations of T cells. Using transient coexpression of p56lck with CD4 or C...
Topics
- Amino Acid Sequence
- Animals
- Antigens, Differentiation, T-Lymphocyte
- CD4 Antigens
- CD8 Antigens
- Cell Line
- Cysteine
- Lymphocyte Specific Protein Tyrosine Kinase p56(lck)
- Lymphocytes
- Mice
- Molecular Sequence Data