Article
Caffeine-resistance in fission yeast is caused by mutations in a single essential gene, crm1+.
Molecular & general genetics : MGG - 15 Jan 1996
Kumada K, Yanagida M, Toda T
Abstract excerpt
Caffeine is a base analogue and is known to affect a wide variety of cellular processes. In order to dissect genetically molecules which mediate the biological effects of caffeine, temperature-sensitive (ts) and caffeine-resistant mutants were isolated from fission yeast, Schizosaccharomyces pomb...
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