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Article

Global analysis of the acid-induced and urea-induced unfolding of staphylococcal nuclease and two of its variants.

Biochemistry - 4 Feb 1997

Ionescu R M, Eftink M R

Abstract excerpt

We have studied the equilibrium unfolding staphylococcal nuclease and two of its variants, V66W and V66W', over two perturbation axes (acid-induced unfolding as a function of urea concentration and urea-induced unfolding as a function of pH). The transitions were monitored by simultaneous measurements of circular dichroism and fluorescence. With this multidimensional array of data (2 perturbation axes and 2...

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Identifiers

PMID: 9033404
DOI: 10.1021/bi9609681

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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