Article
On the physics of thermal-stability changes upon mutations of a protein.
The Journal of chemical physics - 28 Sept 2015
Murakami Shota, Oshima Hiraku, Hayashi Tomohiko, Kinoshita Masahiro
Abstract excerpt
It is of great interest from both scientific and practical viewpoints to theoretically predict the thermal-stability changes upon mutations of a protein. However, such a prediction is an intricate task. Up to now, significantly many approaches for the prediction have been reported in the literature. They always include parameters which are adjusted so that the prediction results can be best fitted to the...
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