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Article

BCL2 translocation frequency rises with age in humans.

13 Sept 1994

Abstract excerpt

The background frequency of t(14;18) (q32;q21) chromosomal translocations at the locus associated with B-cell leukemia/lymphoma-2 (BCL2) was determined from a survey of the peripheral blood lymphocytes (PBLs) of 53 living individuals and from tissues of 31 autopsies by using a nested PCR assay. The translocation was detected in 55% of PBLs and 35% of autopsied spleens with a frequency of between less than 1 to...

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Identifiers

PMID: 8090743
DOI: 10.1073/pnas.91.19.8910

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