Article
Prevalence and frequency of circulating t(14;18)‐MBR translocation carrying cells in healthy individuals
2 Sept 2008
Abstract excerpt
The t(14;18) translocation is a common genetic aberration that can be seen as an early step in pathogenesis of follicular lymphoma (FL). The significance of low level circulating t(14;18)-positive cells in healthy individuals as clonal lymphoma precursors or indicators of risk is still unclear. We determined the age dependent prevalence and frequency of BCL2/IgH rearrangements in 715 healthy individuals ranging...
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