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Article

Ischemic stroke in the elderly. Role of the common factor V mutation causing resistance to activated protein C.

Stroke - 1 Jan 1996

Press R D, Liu X Y, Beamer N, Coull B M

Abstract excerpt

BACKGROUND AND PURPOSE: A common missense mutation in coagulation factor V (Arg 506 Gln) creates phenotypic resistance to the anticoagulant effects of activated protein C and predisposes carriers to venous thrombosis. To assess a correlation between this common hypercoagulable state and ischemic cerebrovascular disease, we have compared the prevalence of this mutation in a group of stroke patients with that in...

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Identifiers

PMID: 8553401
DOI: 10.1161/01.str.27.1.44

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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