Article
Prothrombin G20210A mutation is associated with young-onset stroke: the genetics of early-onset stroke study and meta-analysis.
Stroke - 1 Apr 2014
Jiang Baijia, Ryan Kathleen A, Hamedani Ali, Cheng Yuching, Sparks Mary J, Koontz Deborah, Bean Christopher J, Gallagher Margaret, Hooper W Craig, McArdle Patrick F, O'Connell Jeffrey R, Stine O Colin, Wozniak Marcella A, Stern Barney J, Mitchell Braxton D, Kittner Steven J, Cole John W
Abstract excerpt
BACKGROUND AND PURPOSE: Although the prothrombin G20210A mutation has been implicated as a risk factor for venous thrombosis, its role in arterial ischemic stroke is unclear, particularly among young adults. To address this issue, we examined the association between prothrombin G20210A and ischemic stroke in a white case-control population and additionally performed a meta-analysis. METHODS: From the...
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