Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Prevalence of factor V gene mutation amongst myocardial infarction patients and healthy controls is higher in Sweden than in other countries.

Journal of internal medicine - 1 Mar 1996

Holm J, Zöller B, Berntorp E, Erhardt L, Dahlbäck B

Abstract excerpt

OBJECTIVE: Haemostatic imbalance may be an aetiological factor in the development of acute coronary syndromes. Inherited resistance to activated protein C (APC) is a common disorder associated with hypercoagulability and lifelong risk of venous thrombosis. APC resistance is due to a single mutati...

Topics

Adult
Case-Control Studies
Factor V
Female
Gene Frequency
Humans
Male
Middle Aged
Mutation
Myocardial Infarction
Prevalence
Protein C
Retrospective Studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Risk Factors

Sex Factors

Sweden

Thrombosis

Source

Identifiers

PMID: 8772620
DOI: 10.1046/j.1365-2796.1996.470808000.x

Genes

APC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8772620-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Prevalence of factor V gene mutation amongst myocardial infarction patients and healthy controls is higher in Sweden than in other countries.PMID 8772620Read ↗

Factor V Q506 (resistance to activated protein C) and prognosis after acute coronary syndrome.Semantic proximity Read ↗

Mutation in the gene coding for coagulation factor V and the risk of myocardial infarction, stroke, and venous thrombosis in apparently healthy men.Semantic proximity Read ↗

Association between factor V Leiden, prothrombin G20210A, and methylenetetrahydrofolate reductase C677T mutations and events of the arterial circulatory system: a meta-analysis of published studies.Semantic proximity Read ↗

Multiple thrombophilia mutations as a possible cause of premature myocardial infarction.Semantic proximity Read ↗

Factor V Leiden (resistance to activated protein C) increases the risk of myocardial infarction in young women.Semantic proximity Read ↗

The association of factor V Leiden with myocardial infarction is replicated in 1880 patients with premature disease.Semantic proximity Read ↗

Resistance to activated protein C, the FV:Q506 allele, and venous thrombosis.Semantic proximity Read ↗

Prothrombotic gene variants as risk factors of acute myocardial infarction in young women.Semantic proximity Read ↗

Prevalence of the prothrombin gene variant 20210 G --> A among patients with myocardial infarction.Semantic proximity Read ↗

Polymorphisms in coagulation factors and the risk of recurrent cardiovascular events in men after a first myocardial infarction.Semantic proximity Read ↗

Increased prevalence of the G20210A prothrombin gene variant in acute coronary syndromes without metabolic or acquired risk factors or with limited extent of disease.Semantic proximity Read ↗

Resistance to activated protein C caused by the R506Q mutation in the gene for factor V is a common risk factor for venous thrombosis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.