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Article

Prothrombin G20210A mutant genotype is a risk factor for cerebrovascular ischemic disease in young patients.

Blood - 15 May 1998

De Stefano V, Chiusolo P, Paciaroni K, Casorelli I, Rossi E, Molinari M, Servidei S, Tonali P A, Leone G

Abstract excerpt

The factor II G20210A mutation is a recently identified congenital risk factor for venous thrombosis. Its role in artery disease is still undefined. We investigated 72 patients (35 male and 37 female) with documented ischemic stroke occurred before 50 years of age and without risk factors such as...

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PMID: 9572989

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-9572989-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

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Prothrombin G20210A mutant genotype is a risk factor for cerebrovascular ischemic disease in young patients.PMID 9572989Read ↗

Prothrombin gene G20210-->A transition is a risk factor for cerebral venous thrombosis.Semantic proximity Read ↗

Inherited thrombophilia as a risk factor for the development of ischemic stroke in young adults.Semantic proximity Read ↗

The heterozygous 20210 G/A prothrombin genotype is associated with early venous thrombosis in inherited thrombophilias and is not increased in frequency in artery disease.Semantic proximity Read ↗

The prothrombin 20210A allele is the most prevalent genetic risk factor for venous thromboembolism in the Spanish population.Semantic proximity Read ↗

Prevalence of the prothrombin gene variant (nt20210A) in venous thrombosis and arterial disease.Semantic proximity Read ↗

Association Between the 20210G>A Prothrombin Gene Polymorphism and Arterial Ischemic Stroke in Children and Young Adults-Two Meta-analyses of 3586 Cases and 6440 Control Subjects in Total.Semantic proximity Read ↗

Homozygous prothrombin gene mutation and ischemic cerebrovascular disease: a case report.Semantic proximity Read ↗

Frequency of the 20210 G-->A mutation in the 3'-untranslated region of the prothrombin gene in 35 cases of cerebral venous thrombosis.Semantic proximity Read ↗

[Heterozygous prothrombin gene mutation G20210A and associated diseases].Semantic proximity Read ↗

The prothrombin gene G20210A variant: prevalence in a U.K. anticoagulant clinic populationSemantic proximity Read ↗

Prothrombin G20210A mutation is associated with young-onset stroke: the genetics of early-onset stroke study and meta-analysis.Semantic proximity Read ↗

The prothrombin 20210 G to A variation and thrombosis.Semantic proximity Read ↗

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