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Article

Rac GTPases in human diseases.

Disease markers - 1 Jan 2010

Pai Sung-Yun, Kim Chaekyun, Williams David A

Abstract excerpt

Rho GTPases are members of the Ras superfamily of GTPases that regulate a wide variety of cellular functions. While Rho GTPase pathways have been implicated in various pathological conditions in humans, to date coding mutations in only the hematopoietic specific GTPase, RAC2, have been found to cause a human disease, a severe phagocytic immunodeficiency characterized by life-threatening infections in infancy....

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Source

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Identifiers

PMID: 21178276
DOI: 10.3233/DMA-2010-0738
PMCID: PMC3835286

Genes

RAC2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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