Article
Plant rac proteins induce superoxide production in mammalian cells.
Biochemical and biophysical research communications - 16 Jun 2000
Hassanain H H, Sharma Y K, Moldovan L, Khramtsov V, Berliner L J, Duvick J P, Goldschmidt-Clermont P J
Abstract excerpt
The small GTP-binding protein family including Rac proteins represents a paradigm for signaling molecules shared by animal and plants. In mammalian cells, Rac induces the activation of NADPH oxidase leading to superoxide production. In plants, evidence suggests that resistance to pathogens depends on superoxide that is generated via NADPH oxidase-like enzymes. We have identified four closely related Rho/Rac genes...
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