Article
No evidence for mutations in the alpha- and beta-catenin genes in human gastric and breast carcinomas.
Cancer research - 1 Jan 1996
Candidus S, Bischoff P, Becker K F, Höfler H
Abstract excerpt
Disturbed function of E-cadherin and/or of one of its anchoring proteins, the catenins, is thought to destabilize E-cadherin-mediated cell-cell adhesion, which may enhance the invasiveness of epithelial cells and thus favor carcinoma progression. Reduced expression of E-cadherin and alpha-catenin...
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