Article
Leukaemia inhibitory factor prevents injury induced proliferation of striatal dopamine uptake sites.
Neuroreport - 2 Oct 1995
Howells D W, Wong J Y, Churchyard A J, Donnan G A
Abstract excerpt
The injury associated with implantation of an inert gelatin matrix (gel foam) into normal mouse striatum induces a long-lived increase in binding of [3H]mazindol to presynaptic dopamine uptake sites, probably due to proliferation of striatal dopaminergic terminals. Because of the known effects of leukaemia inhibitory factor (LIF) on catecholaminergic cells, we tested the hypothesis that LIF may alter the striatal...
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