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Article

In vitro studies on the characterization of cellular proliferation following neuronal injury in the adult rat brain.

Journal of neuroimmunology - 1 Jan 2000

Katz I R, Iacovitti L M, Reis D J

Abstract excerpt

While brain injury elicits local cellular proliferation, it is not known whether cells not originating in brain substantially participate in the response. We assessed the time course and phenotype of dividing cells following neuronal damage initiated by microinjection of the neurotoxin ibotenic acid into one caudate nucleus (CN) in adult rat. Proliferation was determined in an in vitro assay measuring...

Topics

Animals
Astrocytes
Blood-Brain Barrier
Brain
Caudate Nucleus
Cell Division
Cells, Cultured
Ibotenic Acid
Leukocytes, Mononuclear
Male
Neurons
Phenotype

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Rats

Rats, Inbred Strains

Source

Identifiers

PMID: 2211987
DOI: 10.1016/0165-5728(90)90145-d

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-2211987-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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