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Article

Differential response of ventral midbrain and striatal progenitor cells to lesions of the nigrostriatal dopaminergic projection.

Developmental neuroscience - 1 Jan 2000

Kay J N, Blum M

Abstract excerpt

In response to injury, progenitor cells in the adult brain can proliferate and generate new neurons and/or glia, which may then participate in injury-induced compensatory processes. In this study, we explore the ability of young adult mice to generate new cells in response to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) lesions, which selectively kill nigrostriatal dopaminergic neurons. Using the thymidine...

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PMID: 10657698
DOI: 10.1159/000017427

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GFAP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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