Article
Serum response element and flanking sequences mediate the synergistic transcriptional activation of c-fos by 12-O-tetradecanoylphorbol-13-acetate and cholera toxin in AKR-2B cells.
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research - 1 Aug 1995
Harvat B L, Wharton W
Abstract excerpt
12-O-Tetradecanoylphorbol-13-acetate (TPA) and cholera toxin have been shown previously to act synergistically to stimulate traverse of G0-G1 and entry into S phase in quiescent mouse fibroblasts. These agents also have a synergistic effect on the induction of the endogenous c-fos gene, as well a...
Topics
- Animals
- Basal Metabolism
- Base Sequence
- Binding Sites
- Cell Line
- Cholera Toxin
- Drug Synergism
- Genes, Reporter
- Genes, fos
- Luciferases
- Mice
- Molecular Sequence Data