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Article

Association of apolipoprotein E epsilon 4 allele with bulbar-onset motor neuron disease.

Lancet (London, England) - 20 Jan 1996

al-Chalabi A, Enayat Z E, Bakker M C, Sham P C, Ball D M, Shaw C E, Lloyd C M, Powell J F, Leigh P N

Abstract excerpt

BACKGROUND: Variants of the apolipoprotein E (APOE) gene influence the age of onset of Alzheimer's disease. APOE may influence the presentation of other neurological diseases. We investigated the relationship between the allelic variants of apolipoprotein E and clinical presentation in motor neuron disease. METHODS: 123 patients with motor neuron disease and 121 controls were studied. Diagnosis, location of onset...

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Source

Identifiers

PMID: 8544551
DOI: 10.1016/s0140-6736(96)90343-8

Genes

APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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