Article
Yeast mutants of glucose metabolism with defects in the coordinate regulation of carbon assimilation.
Archives of biochemistry and biophysics - 15 May 1999
Dennis R A, Rhodey M, McCammon M T
Abstract excerpt
The enzymes of the glyoxylate cycle and gluconeogenesis are tightly regulated by transcriptional, posttranscriptional, and posttranslational mechanisms in Saccharomyces cerevisiae. We have previously identified four genes, ACN8, ACN9, ACN17, and ACN18, whose mutant phenotype includes two- to fourfold elevated levels of enzymes of the glyoxylate cycle, gluconeogenesis, and acetyl-CoA metabolism. The affected...
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