Article
Porcine malignant hyperthermia: genotype and contractile threshold of immature muscles.
Muscle & nerve - 1 Jan 1996
Gallant E M, Jordan R C
Abstract excerpt
We investigated whether malignant hyperthermia (MH)-related contractile abnormalities, such as lowered contractile threshold, were expressed in MH-susceptible (MHS) immature muscles and myotubes. Muscles from neonatal piglets homozygous for Arg615 (normal) or for Cys615 (MHS) ryanodine receptor a...
Topics
- Aging
- Animals
- Animals, Newborn
- Biomechanical Phenomena
- Cells, Cultured
- Differential Threshold
- Genotype
- Heterozygote
- Malignant Hyperthermia
- Muscle Contraction
- Muscles
- Species Specificity
- Stimulation, Chemical
- Swine
