Article
Porcine malignant hyperthermia: genotype and contractile threshold of immature muscles.
Muscle & nerve - 1 Jan 1996
Gallant E M, Jordan R C
Abstract excerpt
We investigated whether malignant hyperthermia (MH)-related contractile abnormalities, such as lowered contractile threshold, were expressed in MH-susceptible (MHS) immature muscles and myotubes. Muscles from neonatal piglets homozygous for Arg615 (normal) or for Cys615 (MHS) ryanodine receptor alleles, and heterozygotes were used. Intact cell bundles from piglet muscles generally were similar in contractile...
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