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Article

Ca2+ release channels of pigs heterozygous for malignant hyperthermia.

Muscle & nerve - 1 Oct 1995

Shomer N H, Mickelson J R, Louis C F

Abstract excerpt

Porcine malignant hyperthermia (MH) is an autosomal recessive disorder resulting from a mutation in the skeletal muscle sarcoplasmic reticulum (SR) Ca2+ release channel. The Ca2+ release properties of SR vesicles isolated from pigs heterozygous for the MH gene have been demonstrated previously to be intermediate to those of vesicles isolated from MH-susceptible (MHS) and normal pigs. The Ca2+ release channel is...

Topics

Animals
Calcium Channels
Heterozygote
Malignant Hyperthermia
Mathematics
Muscle, Skeletal
Mutation
Sarcoplasmic Reticulum
Swine
Swine Diseases
Time Factors

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 7659111
DOI: 10.1002/mus.880181013

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7659111-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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