Article
Ca2+ release channels of pigs heterozygous for malignant hyperthermia.
Muscle & nerve - 1 Oct 1995
Shomer N H, Mickelson J R, Louis C F
Abstract excerpt
Porcine malignant hyperthermia (MH) is an autosomal recessive disorder resulting from a mutation in the skeletal muscle sarcoplasmic reticulum (SR) Ca2+ release channel. The Ca2+ release properties of SR vesicles isolated from pigs heterozygous for the MH gene have been demonstrated previously to be intermediate to those of vesicles isolated from MH-susceptible (MHS) and normal pigs. The Ca2+ release channel is...
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