Article
The Diagnostic Yield of Malignancy Comparing Cytology, FISH, and Molecular Analysis of Cell Free Cytology Brush Supernatant in Patients With Biliary Strictures Undergoing Endoscopic Retrograde Cholangiography (ERC): A Prospective Study.
Journal of clinical gastroenterology - 1 Oct 2019
Kushnir Vladimir M, Mullady Daniel K, Das Koushik, Lang Gabriel, Hollander Thomas G, Murad Faris M, Jackson Sara A, Toney Nicole A, Finkelstein Sydney D, Edmundowicz Steven A
Abstract excerpt
BACKGROUND: Routine cytology of biliary stricture brushings obtained during endoscopic retrograde cholangiopancreatography (ERCP) has suboptimal sensitivity for malignancy. We compared the individual and combined ability of cytology, fluorescence in situ hybridization (FISH) analysis and PCR-based mutation profiling (MP) to detect malignancy in standard biliary brushings. METHODS: We performed a prospective study...
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