Article
Alterations of the retinoblastoma a susceptibility gene in chronic lymphocytic leukemia.
Leukemia & lymphoma - 1 Aug 1995
Neubauer A, Richiero K, Huhn D
Abstract excerpt
Research in recent years has shown that malignant transformation is a genetic multistep process. This holds true not only for in-vitro model systems, but has also been elegantly shown in-vivo, as in colorectal cancer. Chronic lymphocytic leukemia (CLL) is the most frequent leukemia in Western cou...
Topics
- Cell Division
- Chromosomes, Human, Pair 13
- DNA, Neoplasm
- Gene Expression
- Genes, Retinoblastoma
- Humans
- Leukemia, Lymphocytic, Chronic, B-Cell
- Mutation
- RNA, Messenger
- RNA, Neoplasm
- Retinoblastoma Protein