Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Alterations of the retinoblastoma a susceptibility gene in chronic lymphocytic leukemia.

Leukemia & lymphoma - 1 Aug 1995

Neubauer A, Richiero K, Huhn D

Abstract excerpt

Research in recent years has shown that malignant transformation is a genetic multistep process. This holds true not only for in-vitro model systems, but has also been elegantly shown in-vivo, as in colorectal cancer. Chronic lymphocytic leukemia (CLL) is the most frequent leukemia in Western countries and occurs mainly in elderly patients, suggesting that in this form of leukemia, cumulative molecular lesions...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Division
Share to Chromosomes, Human, Pair 13
Share to DNA, Neoplasm

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Gene Expression

Share to Genes, Retinoblastoma

Share to Mutation

Share to RNA, Messenger

Share to RNA, Neoplasm

Source

Identifiers

PMID: 8528045
DOI: 10.3109/10428199509059637

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Alterations of the retinoblastoma a susceptibility gene in chronic lymphocytic leukemia.PMID 8528045Read ↗

Genetic alteration associated with chronic lymphocytic leukemia.Semantic proximity Read ↗

Molecular cytogenetic analysis of RB-1 deletions in chronic B-cell leukemias.Semantic proximity Read ↗

[Genetic changes in chronic lymphocytic leukemia].Semantic proximity Read ↗

Structural alterations at the putative retinoblastoma locus in some human leukemias and preleukemia.Semantic proximity Read ↗

The genetics of retinoblastoma.Semantic proximity Read ↗

Mutations of the retinoblastoma gene in human lymphoid neoplasms.Semantic proximity Read ↗

Deletion of the human retinoblastoma gene in primary leukemias.Semantic proximity Read ↗

Minimal region of loss at 13q14 in B-cell chronic lymphocytic leukemia.Semantic proximity Read ↗

Genetic alterations in chronic lymphocytic leukaemia.Semantic proximity Read ↗

High frequency of monoallelic retinoblastoma gene deletion in B-cell chronic lymphoid leukemia shown by interphase cytogenetics.Semantic proximity Read ↗

DNA repair polymorphisms associated with cytogenetic subgroups in B-cell chronic lymphocytic leukemia.Semantic proximity Read ↗

Evidence for a new tumour suppressor locus (DBM) in human B-cell neoplasia telomeric to the retinoblastoma gene.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.