Article
DNA repair polymorphisms associated with cytogenetic subgroups in B-cell chronic lymphocytic leukemia.
Genes, chromosomes & cancer - 1 Sept 2009
Ganster Christina, Neesen Jürgen, Zehetmayer Sonja, Jäger Ulrich, Esterbauer Harald, Mannhalter Christine, Kluge Britta, Fonatsch Christa
Abstract excerpt
Genetic polymorphisms in DNA repair genes can affect the risk of developing different forms of cancer. Therefore, we have studied the putative association of seven single nucleotide polymorphisms (SNPs) in five DNA repair genes with the incidence of chronic lymphocytic leukemia (CLL). We included 461 CLL patients and the same number of age- and sex-matched controls. As chromosomal aberrations are important...
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