Article
The genetics of retinoblastoma.
Annales de genetique - 1 Jan 1994
Stahl A, Levy N, Wadzynska T, Sussan J M, Jourdan-Fonta D, Saracco J B
Abstract excerpt
Retinoblastoma is a malignant tumor of the eye that affects about one in 20,000 young children and occurs as hereditary and non-hereditary (sporadic) forms. It results from successive loss or inactivation of the two alleles of the Rb1 gene, located in 13q14. A chromosomal deletion in 13q14 is rev...
Topics
- Chromosomes, Human, Pair 13
- Eye Neoplasms
- Genes, Retinoblastoma
- Heterozygote
- Humans
- Karyotyping
- Mutation
- Retinoblastoma
- Retinoblastoma Protein