Article
Molecular cytogenetic analysis of RB-1 deletions in chronic B-cell leukemias.
Leukemia & lymphoma - 1 Dec 1994
Döhner H, Pilz T, Fischer K, Cabot G, Diehl D, Fink T, Stilgenbauer S, Bentz M, Lichter P
Abstract excerpt
Deletions or translocations of 13q, most commonly involving band 13q14, belong to the most frequent structural chromosome abnormalities in B-cell chronic lymphocytic leukemia (B-CLL). In a combined metaphase and interphase cytogenetic study using conventional G-banding analysis and fluorescence i...
Topics
- Adult
- Aged
- Aged, 80 and over
- Alleles
- Chromosome Aberrations
- Chromosome Banding
- Chromosomes, Human, Pair 1
- Chromosomes, Human, Pair 13
- Female
- Gene Deletion
- Genes, Retinoblastoma
- Humans
- In Situ Hybridization, Fluorescence
- Interphase
- Leukemia, B-Cell
- Leukemia, Hairy Cell
- Leukemia, Lymphocytic, Chronic, B-Cell
- Leukemia, Prolymphocytic