Article
Mutations of the retinoblastoma gene in human lymphoid neoplasms.
Leukemia & lymphoma - 1 Aug 1992
Ginsberg A M, Raffeld M, Cossman J
Abstract excerpt
The inactivation or loss of tumor suppressor genes (anti-oncogenes) has been implicated as a mechanism central to the pathogenesis of many solid tumors. More recently, we and others have identified a role of one rumor suppressor gene, the retinoblastoma gene, in the development of human lymphoid lymphoma and leukemia. Here we review the involvement of the retinoblastoma gene in the control of normal lymphocyte...
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