Mutations of the retinoblastoma gene in human lymphoid neoplasms.

doi:10.3109/10428199209049791

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Article

Mutations of the retinoblastoma gene in human lymphoid neoplasms.

Leukemia & lymphoma - 1 Aug 1992

Ginsberg A M, Raffeld M, Cossman J

Abstract excerpt

The inactivation or loss of tumor suppressor genes (anti-oncogenes) has been implicated as a mechanism central to the pathogenesis of many solid tumors. More recently, we and others have identified a role of one rumor suppressor gene, the retinoblastoma gene, in the development of human lymphoid...

Topics

Genes, Retinoblastoma
Humans
Leukemia
Lymphoma
Mutation

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