Article
Prognostic value of mutations in TP53 and RAS genes in breast cancer.
The International journal of biological markers - 1 Jan 2000
Guerra E, Vacca G, Palombo B, Alberti S
Abstract excerpt
The identification of molecular indicators of higher risk for specific subgroups of cancer patients may allow to develop more aggressive therapeutic strategies aimed at cases with the highest likelihood of response. This would avoid unnecessary toxicity to patients and alleviate the burden of cancer care for healthcare systems. Activated oncogenes and mutated tumor suppressor genes are causal determinants of the...
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