Article
Characterization of Mengo virus neutralization epitopes. II. Infection of mice with an attenuated virus.
Virology - 1 Dec 1995
Kobasa D, Mulvey M, Lee J S, Scraba D G
Abstract excerpt
A panel of five neutralizing monoclonal antibodies was generated from mice immunized with an attenuated strain of Mengo virus. Four of the antibodies were used to select mutants of Mengo virus which were able to escape neutralization by the selecting antibody, but it was not possible to select mu...
Topics
- Animals
- Antibodies, Monoclonal
- Antibodies, Viral
- Antigens, Viral
- B-Lymphocytes
- Base Sequence
- DNA, Viral
- Epitopes
- Mengovirus
- Mice
- Mice, Inbred BALB C
- Molecular Sequence Data
- Mutation
