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Article

Characterization of Mengo virus neutralization epitopes. II. Infection of mice with an attenuated virus.

Virology - 1 Dec 1995

Kobasa D, Mulvey M, Lee J S, Scraba D G

Abstract excerpt

A panel of five neutralizing monoclonal antibodies was generated from mice immunized with an attenuated strain of Mengo virus. Four of the antibodies were used to select mutants of Mengo virus which were able to escape neutralization by the selecting antibody, but it was not possible to select mutants which could escape neutralization by the fifth antibody. The capsid coding region of the RNA genome of each...

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Identifiers

PMID: 8525606
DOI: 10.1006/viro.1995.9948

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